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Clinical Observations on the Treatment of Endometriosis by Combined Acupuncture and Herbs

Shanghai Journal of Acupuncture and MoxibustionFu Yu and Xia Tian, Shanghai Jnl Acup Moxa, 2005, Vol 3 Shanghai Journal of Acupuncture and Moxibustion

This is just one trial of many carried out in China which looks at the clinical effectiveness of treatment of endometriosis with acupuncture and Chinese herbs. The investigators report that symptoms  and signs of the disease are treated effectively without side effects.

 

Abstract

Objective

To compare the clinical efficacy of combined acupuncture and herbs with danazol for treatment of endometriosis.

Methods

Seventy-eight patients were randomly divided into a combined acupuncture and herbs treatment group (40 cases) and a Westerm medicine control group (38 cases). Observation was made of changes in clinical symptoms, signs, serum CA 125, β-EP, PGE 2 and PGF 2α, and adverse reaction to the medicine in the two group.

Results

The overall efficacy was similar in the two groups, but the effects on lumbosacral pain, anal downbearing distention, irregular menstruation and infertility were significantly better in the treatment group than in the control group(P < 0.05), and in the treatment group serum CA 125, PGE 2 and PGF 2α were significantly lower and serum β-EP was significanly higher after treatment than before (P < 0.05).

Conclusion

Combined use of acupuncture and herbs has a marked effect on endometriosis and the adverse reaction is lower than the control group.

Clinical Observation of Chinese Medicine Treatment on Secondary Dysmenorrhoea Associated with Endometriosis

Australian Journal of Acupuncture and Chinese Medicine

Australian Journal of Acupuncture and Chinese Medicine

Lim CED et al, Aust J Acupunct Chin Med 2009;4(2):12-17. Australian Journal Acupuncture and Chinese Medicine

Those of us who have experience in treating endometriosis with Chinese medicine are familiar with the benefits it brings patients in terms of reduced pain and possibly increased rates of conception. This pilot study, a collaboration between Guangzhou Medical University in China and RMIT university in Melbourne, is particularly interesting to us since it measured objective parameters such as immune factors (antigens and antibodies) shown to be abnormally raised in patients with endometriosis. A course of treatment with Chinese herbs not only improved pain but significantly reduced the levels of these immune factors. This is one way that Chinese medicine may improve fertility in endometriosis.

 

Abstract

Background

Secondary dysmenorrhoea associated with endometriosis affects many women and is the leading cause of work and school absenteeism, with considerable impact on quality of life. This study evaluates the possible role of Chinese medicinal herbs in relieving the menstrual pain associated with endometriosis.

 

Methods

A prospective clinical observational pilot study involving twenty-five patients with endometriosis with Chinese medical diagnosis of stagnation of qi and blood who were recruited at the Guangdong Women’s and Children’s Hospital during the period of January 2004 to December 2006 to participate in a three-month Chinese medicinal herbs study.

 

Results

Sixteen patients reported nil dysmenorrhoea during the treatment period. The mean CA125 at the study entry was 59.67 ±28.32 u/ml, compared to 34.83 ±16.34 u/ml post-treatment. The positive EMAb before the commencement of treatment was noted in 22 of 25 cases (88%), while 5 of 25 cases (20%) remained positive after treatment.

 

Conclusion

Short-term administration of Chinese medicinal herbs may be effective in alleviating secondary dysmenorrhoea associated with endometriosis in qi and blood stagnation pattern. It may provide an alternative treatment option for the management of pelvic pain associated with endometriosis and further research in the area is required.

ACUPUNCTURE, HERBS AND ENDOMETRIOSIS: Complementary and Alternative Medicine for Endometriosis: A Review of Utilisation and Mechanism

ACUPUNCTURE, HERBS AND ENDOMETRIOSIS: Complementary and Alternative Medicine for Endometriosis: A Review of Utilisation and Mechanism

Evidence-Based-Complementary-and-Alternative-Medicine

Evidence-Based-Complementary-and-Alternative-Medicine

Kong S et al, Volume (2014), Article ID 146383, 16 pages Evidence-Based Comp and Altern Med Evidence-Based Complementary and Alternative Medicine

This very thorough review compares results of treatment of endometriosis with acupuncture or herbal therapies and pharmaceutical or surgical approaches. A number of therapies, including using Chinese herbs per rectum, obtained great relief for patients, but without the side effects caused by drugs or surgery.

Abstract

Endometriosis (EM) is one of the common gynecological conditions causing menstrual and pelvic pain and affects 10%–15% of women of reproductive age. In recent years, the complementary and alternative medical (CAM) treatment for EM has become popular due to the few adverse reactions reported. The CAM therapy for EM includes several different treatments such as herbs (herbal prescription, extract, and patent), acupuncture, microwave physiotherapy, and Chinese herb medicine enema (CHM enema). These CAM therapies are effective at relieving dysmenorrhoea, shrinking adnexal masses, and promoting pregnancy, with less unpleasant side effects when compared to hormonal and surgical treatments. In this review, we focus on the status quo of CAM on EM and try to identify therapeutic efficacy and mechanisms based on some clinical and experimental studies. We hope to provide some instructive suggestions for clinical treatment and experimental research in the future. 

Acupuncture Combined with Herbal Medicine Effects on Outcomes of Patients with Endometriosis Who Accepted IVF-ET

Liaoning Chinese Medicine Journal

Acupuncture & Herbal Medicine Boost IVF Success in Endometriosis Patients

In a study conducted in northeastern China, 180 women diagnosed with endometriosis undergoing IVF treatments were divided into three groups. The study aimed to determine the impact of acupuncture and Chinese herbal medicine on IVF outcomes.

The Findings:

  1. The acupuncture combined with herbal medicine group had notably higher pregnancy rates compared to those who did not receive acupuncture.
  2. Among the three groups undergoing IVF, the one with acupuncture and herbal medicine showed significantly better outcomes in terms of oocyte retrieval, fertilization rates, implantation success, and overall pregnancy rates.
  3. The patients receiving acupuncture combined with herbal medicine reported better satisfaction scores than those only receiving medicine.

Conclusion: The study concludes that the use of acupuncture alongside herbal medicine had a substantial positive impact on IVF outcomes for women with endometriosis. This combined approach proved more effective than solely using medicine during IVF treatments.

Acupuncture for Pain Research

Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture

Nanna Goldman, Michael Chen, Takumi Fujita, Qiwu Xu, Weiguo Peng, Wei Liu, Tina K Jensen, Yong Pei, Fushun Wang, Xiaoning Han, Jiang-Fan Chen, Jurgen Schnermann, Takahiro Takano, Lane Bekar, Kim Tieu & Maiken Nedergaard

Nature Neuroscience 13, 883–888 (2010) doi:10.1038/nn.2562 2010 Published online 30 May 2010

Abstract

Acupuncture is an invasive procedure commonly used to relieve pain. Acupuncture is practiced worldwide, despite difficulties in reconciling its principles with evidence-based medicine. We found that adenosine, a neuromodulator with anti-nociceptive properties, was released during acupuncture in mice and that its anti-nociceptive actions required adenosine A1 receptor expression. Direct injection of an adenosine A1 receptor agonist replicated the analgesic effect of acupuncture. Inhibition of enzymes involved in adenosine degradation potentiated the acupuncture-elicited increase in adenosine, as well as its anti-nociceptive effect. These observations indicate that adenosine mediates the effects of acupuncture and that interfering with adenosine metabolism may prolong the clinical benefit of acupuncture.