Coburg 03 9378 9479 Ringwood 03 8802 1519

Recurrent miscarriage–outcome after supportive care in early pregnancy

Recurrent miscarriage–outcome after supportive care in early pregnancy Liddell HS et al, Aust N Z J Obstet Gynaecol. 1991 Nov;31(4):320-2. This study did not use acupuncture or herbs, but it is interested to include it here as a way of managing early pregnancy in women who have had previous miscarriages. There is currently no known prevention therapy for unexplained recurrent miscarriage, but this study showed that emotional support and close supervision helped improve outcomes in subsequent pregnancies.     Abstract One hundred and thirty three couples were investigated at a recurrent miscarriage clinic. In their next pregnancy 42 women (Group 1) with unexplained recurrent miscarriage were managed with a programme of formal emotional support and close supervision at an early pregnancy clinic. Two women were seen in 2 pregnancies (44 supervised pregnancies); 86% (38 of 44) of these pregnancies were successful. Four of the 6 miscarriages had an identifiable causal factor. Nine women (Group 2), also with unexplained recurrent miscarriage, acted as a control group. After initial investigation they were reassured and returned to the care of their family practitioner and did not receive formal supportive care in their subsequent pregnancy; 33% (3 of 9) of these pregnancies were successful (p = 0.005; Fishers Exact Test). Whilst acknowledging that there is a significant spontaneous cure rate in this condition, emotional support seems to be important in the prevention of unexplained recurrent miscarriage, giving results as good as any currently accepted...

Effect of Quyu Jiedu Granule (祛瘀解毒颗粒) on Micro environment of Ova in Patients with Endometriosis

Effect of Quyu Jiedu Granule (祛瘀解毒颗粒) on Micro environment of Ova in Patients with Endometriosis Lian Fang et al, Zhong Xi Yi He Xue Bao 2009 Feb;15(1):42-46 Chinese Journal of Integrated Medicine A chinese herb formula for endometriosis was given to women with  long term infertility and endometriosis before and during an IVF cycle and various ovarian parameters were compared with a group of women with endometriosis who embarked on IVF directly without taking the herbs. The group who took the herbs produced more eggs and had a higher fertilisation rate (although a difference in pregnancy rate was not reported). Additionally the follicles of the women who took the herbs showed a reduced level of inflammatory cytokines compared to the women in the control group.     Abstract Objective: To observe the effect of Quyu Jiedu Granules (QJG) on the microenvironment of ova in patients with endometriosis (EM). Methods: Twenty EM patients who received in vitro fertilization and embryo transfer (IVF-ET) were randomized equally into a treated group and a control group. Further, 20 patients who received IVF-ET due to oviduct factors were enrolled into a non-endometriosis group. The dosage of gonadotrophic hormone used, the number of ova attained, fertilization rate and clinical pregnancy rate were all observed, and the levels of tumor necrosis factor α (TNF-α) and interleukin 6 (IL-6) in follicular fluid as well as their mRNA expressions in ovarian granular cells were detected by RT-PCR on the very day of ovum attainment. Results: The ova attainment (13.80±6.87) and fertilization rate (0.69±0.31) in the treated group were all higher than the corresponding values in the control group (9.80±5.32 and 0.47±0.22); the...

Clinical Observations on the Treatment of Endometriosis by Combined Acupuncture and Herbs

Clinical Observations on the Treatment of Endometriosis by Combined Acupuncture and Herbs Fu Yu and Xia Tian, Shanghai Jnl Acup Moxa, 2005, Vol 3 Shanghai Journal of Acupuncture and Moxibustion This is just one trial of many carried out in China which looks at the clinical effectiveness of treatment of endometriosis with acupuncture and Chinese herbs. The investigators report that symptoms  and signs of the disease are treated effectively without side effects.   Abstract Objective: To compare the clinical efficacy of combined acupuncture and herbs with danazol for treatment of endometriosis. Methods: Seventy-eight patients were randomly divided into a combined acupuncture and herbs treatment group (40 cases) and a Westerm medicine control group (38 cases). Observation was made of changes in clinical symptoms, signs, serum CA 125, β-EP, PGE 2 and PGF 2α, and adverse reaction to the medicine in the two group. Results: The overall efficacy was similar in the two groups, but the effects on lumbosacral pain, anal downbearing distention, irregular menstruation and infertility were significantly better in the treatment group than in the control group(P < 0.05), and in the treatment group serum CA 125, PGE 2 and PGF 2α were significantly lower and serum β-EP was significanly higher after treatment than before (P < 0.05). Conclusion: Combined use of acupuncture and herbs has a marked effect on endometriosis and the adverse reaction is lower than the control...

Clinical Observation of Chinese Medicine Treatment on Secondary Dysmenorrhoea Associated with Endometriosis

Clinical Observation of Chinese Medicine Treatment on Secondary Dysmenorrhoea Associated with Endometriosis Lim CED et al, Aust J Acupunct Chin Med 2009;4(2):12-17. Australian Journal Acupuncture and Chinese Medicine     Those of us who have experience in treating endometriosis with Chinese medicine are familiar with the benefits it brings patients in terms of reduced pain and possibly increased rates of conception. This pilot study, a collaboration between Guangzhou Medical University in China and RMIT university in Melbourne, is particularly interesting to us since it measured objective parameters such as immune factors (antigens and antibodies) shown to be abnormally raised in patients with endometriosis. A course of treatment with Chinese herbs not only improved pain but significantly reduced the levels of these immune factors. This is one way that Chinese medicine may improve fertility in endometriosis. Abstract Background: Secondary dysmenorrhoea associated with endometriosis affects many women and is the leading cause of work and school absenteeism, with considerable impact on quality of life. This study evaluates the possible role of Chinese medicinal herbs in relieving the menstrual pain associated with endometriosis. Methods: A prospective clinical observational pilot study involving twenty-five patients with endometriosis with Chinese medical diagnosis of stagnation of qi and blood who were recruited at the Guangdong Women’s and Children’s Hospital during the period of January 2004 to December 2006 to participate in a three-month Chinese medicinal herbs study. Results: Sixteen patients reported nil dysmenorrhoea during the treatment period. The mean CA125 at the study entry was 59.67 ±28.32 u/ml, compared to 34.83 ±16.34 u/ml post-treatment. The positive EMAb before the commencement of treatment was noted in 22 of 25...

ACUPUNCTURE, HERBS AND ENDOMETRIOSIS: Complementary and Alternative Medicine for Endometriosis: A Review of Utilisation and Mechanism

ACUPUNCTURE, HERBS AND ENDOMETRIOSIS: Complementary and Alternative Medicine for Endometriosis: A Review of Utilisation and Mechanism Kong S et al, Volume (2014), Article ID 146383, 16 pages Evidence-Based Comp and Altern Med Evidence-Based Complementary and Alternative Medicine This very thorough review compares results of treatment of endometriosis with acupuncture or herbal therapies and pharmaceutical or surgical approaches. A number of therapies, including using Chinese herbs per rectum, obtained great relief for patients, but without the side effects caused by drugs or surgery.   Abstract Endometriosis (EM) is one of the common gynecological conditions causing menstrual and pelvic pain and affects 10%–15% of women of reproductive age. In recent years, the complementary and alternative medical (CAM) treatment for EM has become popular due to the few adverse reactions reported. The CAM therapy for EM includes several different treatments such as herbs (herbal prescription, extract, and patent), acupuncture, microwave physiotherapy, and Chinese herb medicine enema (CHM enema). These CAM therapies are effective at relieving dysmenorrhoea, shrinking adnexal masses, and promoting pregnancy, with less unpleasant side effects when compared to hormonal and surgical treatments. In this review, we focus on the status quo of CAM on EM and try to identify therapeutic efficacy and mechanisms based on some clinical and experimental studies. We hope to provide some instructive suggestions for clinical treatment and experimental research in the...

Acupuncture Combined with Herbal Medicine Effects on Outcomes of Patients with Endometriosis Who Accepted IVF-ET

Acupuncture Combined with Herbal Medicine Effects on Outcomes of Patients with Endometriosis Who Accepted IVF-ET Yu Xiao-Li et al, Liaoning Journal of Traditional Chinese Medicine 2010 Vol 4 Liaoning Journal of Traditional Chinese Medicine This clinical trial carried out in north east China, recruited 180 women diagnosed with endometriosis who were doing a long down regulated IVF protocol. The women who were given acupuncture and chinese herbal medicine achieved significantly higher pregnancy rates than those in the other groups who did not have acupuncture. Abstract (English version) Objective: We investigated the effect of the intervention of acupuncture combined with herbal medicine on outcomes of patients with endometriosis (EM) who accepted in vitro fertilization-embryo transfer (IVF-ET). Methods: 180 cases from patients who took IVF-ET were randomly assigned into three groups,the control group(60 cases),the medicine group(60 cases),and the acupuncture combined with medicine group(60 cases).All the three groups were introduced with gonadotropin releasing hormone agonist(GnRH a) long protocol,and the curative effects were compared between groups. Results: The total effective rate, number of retrieved oocytes, rate of fertilization, implantation rate, and pregnant rate in the acupuncture combined with medicine group were all higher than those in the medicine group, which there were significant statistical differences(P0.05). The scores of the patients who accepted treatment in the two groups had significant difference (P0.05). Conclusion: Treatment of acupuncture combined with herbal medicine has remarkable effect on the patients who took IVF for ET, which is better than the medicine...